Natriuretic Peptide Assays Revisited
نویسندگان
چکیده
منابع مشابه
Natriuretic Peptide Assays Revisited
Discovery of the endocrine function of the heart (1), which exerts a fundamental role in regulating cardiovascular homeostasis through atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP), has opened up a new field of research that has resulted in multiple clinical applications (2). The human BNP gene encodes for a pre-proBNP olecule of 134 amino acid residues, including a sign...
متن کاملQuality specifications for B-type natriuretic peptide assays.
BACKGROUND The objective of this report is to improve the quality of immunochemical measurements of B-type natriuretic peptide (BNP) and its N-terminal propeptide (NT-proBNP). The recommendations proposed are intended for use by manufacturers of commercial assays, by clinical laboratories using those assays, by clinical trial groups and research investigators, and by regulatory agencies, such a...
متن کاملPerformance characteristics of four automated natriuretic peptide assays.
Measurement of circulating B-type natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) can identify patients with heart failure and guide therapy. The limit of detection, linearity, imprecision, method comparison, analytic concordance, and reference intervals of the Access 2 BNP (Biosite, San Diego, CA), ADVIA Centaur BNP (Bayer Diagnostics, Tarrytown, NY), AxSYM BNP (Abbott Diagnostics,...
متن کامل[Clinical applications of B-type natriuretic peptide assays].
The natriuretic peptide system is activated every time the heart is subjected to injury, whether acute or chronic, as a compensatory mechanism for the effects of vasoconstriction changes that take place in these situations. The primary role of the system is to promote urine output and vasodilation. It is known, however, that a series of additional effects are triggered when these peptides are r...
متن کاملEvaluation of Serum Levels of N-terminal Pro Brain Natriuretic Peptide and Atrial Natriuretic Peptide in Neonates with Respiratory Distress
Background: Acute respiratory distress (ARD) is a critical respiratory failure due to lung injury of neonates leading to the clinical appearance of poor lung compliance. The aimed of the study was to evaluate the diagnostic values in differentiating respiratory from heart diseases with using of N-terminal pro brain natriuretic peptide (NT-pro BNP) and Atrial natriuretic peptide(ANP) in neonates...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2011
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2010.09.075